Prevalence of elevated alanine transaminase activity in dogs treated with CCNU (Lomustine)
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چکیده
منابع مشابه
Is CCNU (lomustine) valuable for treatment of cutaneous epitheliotropic lymphoma in dogs? A critically appraised topic
BACKGROUND CCNU and other treatment protocols are commonly offered to owners for the treatment of dogs diagnosed with cutaneous (epitheliotropic) T-cell lymphoma (CTCL). Chemotherapy protocols provide variable benefits; they have different side-effects, and they typically require monitoring to detect drug toxicity at a non-negligible cost to the owner. At this time, even though CCNU is most oft...
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responsive to changes in the balance between protein anabolism and catabolism. The activity of this enzyme is low when conservation of protein is required for body growth. Thus, in the livers of immature rats, alanine transaminase is only one-fourth the level of that found in adult rat liver (11). Conversely, alanine transaminase activity in liver may be elevated by as much as sevenfold when gl...
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ژورنال
عنوان ژورنال: Veterinary and Comparative Oncology
سال: 2009
ISSN: 1476-5810,1476-5829
DOI: 10.1111/j.1476-5829.2009.00197.x